Radio-Mimetic Chemicals

For mankind as a whole, a possession infinitely more valuable than individual life is our genetic heritage, our link with past and future. Shaped through long aeons of evolution, oru genes not only make us what we are, but hold in their minute beings the future – be it one of promise or threat. Yet generic deterioration through man-made agents is the menace of our time, ‘the last and greatest danger to our civilization.’ Again, the parallel between chemicals and radiation is exact and...

 Computer Metaphors for Biochemistry

The metaphor of the computer represents in some crude fashion the chemistry of life. Nowadays one may assume that the average citizen of an industrialized country is at least as familiar with computers as with rain forests. The idea of using the computer as a metaphor is a natural one. A computer is a device for handling information according to a program which it is able to remember and execute. A living cell, to remain in control of its vital functions in a variable environment, must also p...

 How to Resurrect a Species

The genome of a closely related species will have a high proportion of identical DNA, so it can serve as a blueprint, or “scaffold.” The passenger pigeon’s closest genetic relative is the band-tailed pigeon, which Shapiro is now sequencing. By comparing the fragments of passenger-pigeon DNA with the genomes of similar species, researchers can assemble an approximation of an actual passenger-pigeon genome. [...] Next the genome will have to be inscribed into a living cell... Molecular ...

 The Chemistry of the Nucleus is Just the Metal for the Gears

For it is not cell nuclei, not even individual chromosomes, but certain parts of certain chromosomes from certain cells that must be isolated and collected in enormous quantities for analysis; that would be the precondition for placing the chemist in such a position as would allow him to analyse [the hereditary material] more minutely than [can] the morphologists ... For the morphology of the nucleus has reference at the very least to the gearing of the clock, but at best the chemistry of the...